Brentford have already notched positive results against both Manchester clubs and Chelsea this season.
A trip to the Gtech Community Stadium is one of the trickier away days in the Premier League, with a raucous atmosphere and a hard-fighting Bees team.
Tottenham have four away wins in 11 matches across all competitions this term.
Antonio Conte is without Hugo Lloris, Cristian Romero, Ivan Perisic, Richarlison and Rodrigo Bentancur. Ryan Sessegnon is doubtful.
Both Teams To Score: Yes
Tottenham haven’t kept a clean sheet in eight matches, with both teams to score landing in six of those fixtures.
BTTS has hit in 67 per cent of Spurs’ league matches this season, and in five of 15 for Brentford, including each of their last four in all competitions.
Brentford will be more adventurous than some of their mid-table peers when facing the top sides, which only increases the chances of both teams scoring.
Last time out, Brentford stunned Manchester City at the Etihad. Thomas Frank is able to name an unchanged side for this matchup, with Ivan Toney and Bryan Mbeumo fit to lead the line.
Lloris, Bentancur and Romero are major absentees for Spurs, which could see the Lilywhites become more vulnerable at the back.
Brentford have minimal fatigue to worry about after the World Cup, and look a good bet at this price.
Anytime Goalscorer: Ivan Toney
Scorer of 11 goals this season and three in two matches before the World Cup, Toney has been a handful for defenders all season. He has fired off 20 shots in his last five starts.
Of the league’s top 10 goalscorers, only Erling Haaland has contributed a higher percentage of his team’s goals.
If Brentford are to pull off another win against top six opposition, it is very likely Toney is at the forefront.
All odds are subject to change