The match at Hampden Park was supposed to take place on March 24, but was suspended due to the ongoing conflict in Ukraine.
The Ukrainian Premier League season was terminated as a result, meaning Ukraine’s domestic-based players have not played competitively for months.
But Oleksandr Zinchenko, who won the Premier League title with Manchester City earlier this month, believes the importance of the occasion will compensate for their lack of match practice.
“This game is one of the most important games in my life. The guys look ready and it’s not necessary to talk about motivation.”Oleksandr Zinchenko
He is joined in the squad by Everton defender Vitaliy Mykolenko and West Ham forward Andriy Yarmalenko.
Match Odds: Scotland to win
Ukraine have drawn five and won two of their last seven matches, with both victories coming away from home, against Finland and Bosnia-Herzegovina respectively.
But Scotland, who are unbeaten in their last eight matches and boast home advantage, are favourites to win.
Prior to drawing in friendlies against Poland and Austria in March, Steve Clarke’s side won their previous six matches – all of them World Cup qualifiers – to seal their place in these play-offs.
A seventh successive competitive victory would take the Tartan Army to within one game of qualifying for this year’s World Cup in Qatar.
They will be without injured Arsenal defender Kieran Tierney, although captain Andy Robertson is available, having played in Liverpool’s 1-0 Champions League final defeat to Real Madrid on Saturday.
First Goalscorer: Che Adams
Southampton striker Che Adams is the player most likely to break the deadlock, having netted four times in 15 internationals since making his Scotland debut last year.