Minnesota are playing their third game in London and have won on their two previous visits.
New Orleans also has a perfect record in the capital, and both teams last played in London in 2017.
This is the first of three NFL London games in 2022, which will be followed by the Seahawks and Buccaneers playing in Munich in November.
The Vikings and Saints haven’t played since Christmas Day in 2020, when spectacular performances from Drew Brees and Alvin Kamara led New Orleans to a 52-33 win.
Winner: Minnesota Vikings
The Vikings offence had a blip against the Philadelphia Eagles (the only undefeated team in the NFL), but they put up 23 points against the Green Bay Packers and 28 against the Detroit Lions. Kirk Cousins doesn’t need to be spectacular to put up points with the array of weapons at his disposal.
New Orleans have scored 24 points over their last two games. The defence ranks in the top 10 in yards per play, but they aren’t putting sufficient pressure on the quarterback. Give Cousins time, and he will be able to make plays.
Player Rushing Yards: Alvin Kamara Over 53
Only eight teams allowed more rushing yards than the Vikings through the first three weeks. Alvin Kamara is dealing with a rib issue, but he put up 61 yards on the ground against the Panthers in Week 3 and will see a lot of the ball on Sunday afternoon.
There are some concerns about the Saints’ offensive line, and with good reason, but Minnesota are below average at stopping the run. Kamara had 69.1 rushing yards per game last season – he’s good value to go over 53 this weekend.
Total Points: Under 43
It has been a low-scoring start to the season. League-wide, the under has hit over 60 per cent of the time, and that trend is represented by the Vikings and Saints both going under the points total in two of their three games thus far.
There is a good chance of considerable rain in London on Sunday. Both of these teams are in the bottom 10 in rushing frequency, but that could change if passing plays become trickier. More plays on the ground generally leads to a lower points total.
Add in the Saints’ offensive woes thus far and it’s hard to see how this game gets into the mid-forties.
All odds are subject to change